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发布于:2017-11-20 20:37:48  访问:9 次 回复:0 篇
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We utilised descriptive statistics for example frequencies, proportions and implies to Lly proved crucial. She felt that the describe the distribution of demographic qualities and reports of person symptoms, symptom load and general function. Tiredness was also probably the most regularly reported symptom at follow-up, reported by 67 patients (48.2 ), followed by sleep problems and headache reported by 38.eight and 38.1 , respectively.Is study. Out with the 139, 91 (65.five ) have been women. The median age was 59 years (range 185), with distribution: 189 years, ten.eight ; 409 years, 15.eight ; 509 years, 26.6 ; 609 years, 32.4 ; and 705 years, 14.four . At the least 1 mildly bothersome symptom (severity level I) was reported by 118/139 (84.9 ) sufferers at baseline and by 119 (85.six ) at follow-up (Figure 1(A)). At these two time points, 25 (18.0 ) and 33 (23.7 ) reported ten symptoms or more, respectively. The imply number of at the least mildly bothersome symptoms was five.four at baseline and six.2 following 1 year (p 0.01). No less than moderately bothersome symptoms (severity level II) were reported by 76/139 (54.7 ) at baseline and 79 (56.8 ) at follow-up (Figure 1(B)). At these time points, 3 (two.two ) and eight (5.eight ) patients reported ten symptoms or more, respectively. At baseline, sufferers reported a mean of 1.six level II symptoms, compared with two.3 symptoms a single year later (p 0.02). Severely bothersome symptoms (severity level III) have been significantly less often reported (Figure 1(C)). At baseline, 19/139 (13.7 ) reported at the least one symptom, compared to 27 (19.four ) at follow-up. This raise was not statistically significant. There had been no significant variations in symptom load or general function among the 3 treatmentStatistical analysesSample size calculation was produced for the key outcome on the RCT, the median duration of EM in every single therapy group. The unadjusted sample size was 46 in every single group, altogether 138 sufferers. We made use of descriptive statistics which include frequencies, proportions and suggests to describe the distribution of demographic characteristics and reports of individual symptoms, symptom load and basic function. Two-sample test of proportions was made use of to examine changes in these reports more than time. All p values had been two-sided and values below 0.05 were viewed as statistical important. Following analyses ruling out multicollinearity, multivariate linear regression analyses and analysis of variance (ANOVA) tests were applied to assess the degree of which symptom load and basic function at baseline explained variance in these variables at follow-up. To describe adjustments in reports of person symptoms from baseline to follow-up, we utilised a multi-state model and calculated the transition probabilities for each and every symptom. The numbers of symptoms reported to be severely bothersome amongst sufferers clinically diagnosed with EM at baseline and at the 1year follow-up (n 139).groups neither at baseline or at follow-up, nor at any levels of severity. The common function was reported "as usual" for 98 individuals (70.five ) at baseline, compared with 95 (68.three ) a single year later. At baseline, 5 patients (three.6 ) reported severely reduced basic function, compared with seven (five.0 ) just after one particular year.
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